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Rofo. 2014 May;186(5):501-7. doi: 10.1055/s-0033-1355546. Epub 2014 Feb 4.

Magnetic resonance imaging-guided prostate biopsy: institutional analysis and systematic review.

Author information

1
Department of Biomedical Imaging and Image-guided Therapy, Division of Molecular and Gender Imaging, Medical University of Vienna.
2
Department of Urology, Medical University of Vienna.
3
Department of Pathology, Medical University of Vienna.

Abstract

OBJECTIVES:

To evaluate the detection rate of prostate cancer (PCa) after magnetic resonance-guided biopsy (MRGB); to monitor the patient cohort with negative MRGB results and to compare our own results with other reports in the current literature.

MATERIALS AND METHODS:

A group of 41 patients was included in this IRB-approved study and subjected to combined MRI and MRGB. MRGB was performed in a closed 1.5 T MR unit and the needle was inserted rectally. The follow-up period ranged between 12 and 62 months (mean 3.1 years). To compare the results with the literature, a systematic literature search was performed. Eighteen publications were evaluated.

RESULTS:

The cancer-suspicious regions were punctured successfully in all cases. PCa was detected in eleven patients (26.9 %) who were all clinically significant. MRGB showed a benign histology in the remaining 30 patients. In the follow-up (mean 3.1 years) of patients with benign histology, no new PCa was diagnosed. The missed cancer rate during follow-up was 0.0 % in our study.

CONCLUSION:

MRGB is effective for the detection of clinically significant cancer, and this is in accordance with the recent literature. In the follow-up of patients with benign histology, no new PCa was discovered. Although the probability of developing PCa after negative MRGB is very low, active surveillance is reasonable.

PMID:
24497092
DOI:
10.1055/s-0033-1355546
[Indexed for MEDLINE]
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