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Analyst. 2014 Apr 7;139(7):1632-6. doi: 10.1039/c3an02359a.

Non-invasive mouthguard biosensor for continuous salivary monitoring of metabolites.

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Department of NanoEngineering, University of California, 9500 Gilman Drive, La Jolla, San Diego, CA 92093-0448, USA.


The present work describes the first example of a wearable salivary metabolite biosensor based on the integration of a printable enzymatic electrode on a mouthguard. The new mouthguard enzymatic biosensor, based on an immobilized lactate oxidase and a low potential detection of the peroxide product, exhibits high sensitivity, selectivity and stability using whole human saliva samples. Such non-invasive mouthguard metabolite biosensors could tender useful real-time information regarding a wearer's health, performance and stress level, and thus hold considerable promise for diverse biomedical and fitness applications.

[Indexed for MEDLINE]

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