Format

Send to

Choose Destination
Neurology. 2014 Mar 4;82(9):784-92. doi: 10.1212/WNL.0000000000000162. Epub 2014 Jan 31.

Factors affecting cognitive outcome in early pediatric stroke.

Author information

1
From University Children's Hospital Berne (M. Studer, E.W., T.H., M. Steinlin); Center for Cognition, Learning and Memory (M. Studer, T.H., M. Steinlin), University of Berne; University Children's Hospital Zürich (E.B., A.H.); Children's Hospital Aarau (A.C.M.); University Children's Hospital Basel (A.D.); University Children's Hospital Geneva (J.F.); Children's Hospital Neuchâtel (D.M.); Children's Hospital Chur (E.K.); Children's Hospital St. Gallen (O.M.); Children's Hospital Sion (J.-P.M.); Children's Hospital Bellinzona (G.-P.R.); University Children's Hospital Lausanne (C.P.); Children's Hospital Winterthur (R.S.); and Children's Hospital Lucerne (T.S.-M.), Switzerland.

Abstract

OBJECTIVE:

We examined cognitive performance in children after stroke to study the influence of age at stroke, seizures, lesion characteristics, neurologic impairment (NI), and functional outcome on cognitive outcome.

METHODS:

This was a prospectively designed study conducted in 99 children who sustained an arterial ischemic stroke (AIS) between the age of 1 month and 16 years. All children underwent cognitive and neurologic follow-up examination sessions 2 years after the insult. Cognitive development was assessed with age-appropriate instruments.

RESULTS:

Although mean cognitive performance was in the lower normative range, we found poorer results in subtests measuring visuoconstructive skills, short-term memory, and processing speed. Risk factors for negative cognitive outcome were young age at stroke, seizures, combined lesion location (cortical and subcortical), as well as marked NI.

CONCLUSIONS:

We recommend that all children with a history of AIS undergo regularly scheduled neuropsychological assessment to ensure implementation of appropriate interventions and environmental adjustments as early as possible.

Comment in

PMID:
24489131
DOI:
10.1212/WNL.0000000000000162
[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for HighWire Icon for Zurich Open Access Repository and Archive
Loading ...
Support Center