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Brain Stimul. 2014 Mar-Apr;7(2):151-7. doi: 10.1016/j.brs.2013.10.006. Epub 2013 Oct 31.

Review of the effectiveness of transcranial magnetic stimulation for post-traumatic stress disorder.

Author information

1
Department of Psychiatry, Geisel School of Medicine at Dartmouth, One Medical Center Drive, Lebanon, New Hampshire, USA. Electronic address: Ethan.Karsen@hitchcock.org.
2
Department of Psychiatry, Geisel School of Medicine at Dartmouth, One Medical Center Drive, Lebanon, New Hampshire, USA; Department of Psychiatry, Veterans Affairs National Center for Patient Safety, White River Junction, Vermont, USA.
3
Department of Psychiatry, Geisel School of Medicine at Dartmouth, One Medical Center Drive, Lebanon, New Hampshire, USA; Department of Surgery, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire, USA.

Abstract

BACKGROUND:

Post-traumatic stress disorder (PTSD) is a psychiatric condition with significant morbidity and limited treatment options. Transcranial magnetic stimulation (TMS) has been shown to be an effective treatment for mental illnesses including major depressive disorder.

OBJECTIVE:

Review effectiveness of TMS for PTSD.

METHODS:

Literature review with descriptions of primary studies as well as meta-analysis of studies with a control group.

RESULTS:

Eight primary studies were identified and three studies met criteria for meta-analysis. All studies suggest effectiveness of TMS for PTSD. Additionally, right-sided may be more effective than left-sided treatment, there is no clear advantage in high versus low frequency, and the treatment is generally well tolerated. Meta-analysis shows significant effect size on PTSD symptoms that may be correlated with total number of stimulations.

CONCLUSIONS:

TMS for PTSD appears to be an effective and well-tolerated treatment that warrants additional study to further define treatment parameters, course, and side effects.

KEYWORDS:

Post-traumatic stress disorder; Repetitive transcranial magnetic stimulation; Transcranial magnetic stimulation

PMID:
24486424
DOI:
10.1016/j.brs.2013.10.006
[Indexed for MEDLINE]

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