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Semin Immunol. 2014 Oct;26(5):357-68. doi: 10.1016/j.smim.2014.01.003. Epub 2014 Jan 31.

Neuroendocrine regulation of inflammation.

Author information

1
The Biomedical Sciences Graduate Program, The Ohio State University Wexner College of Medicine, Columbus, OH 43210, United States. Electronic address: padro.5@osu.edu.
2
The Department of Molecular Virology, Immunology, and Medical Genetics, The Ohio State University Wexner College of Medicine, Columbus, OH 43210, United States; The Institute of Behavioral Medicine Research, The Ohio State University Wexner College of Medicine, Columbus, OH 43210, United States. Electronic address: Virginia.sanders@osumc.edu.

Abstract

The interaction between the sympathetic nervous system and the immune system has been documented over the last several decades. In this review, the neuroanatomical, cellular, and molecular evidence for neuroimmune regulation in the maintenance of immune homeostasis will be discussed, as well as the potential impact of neuroimmune dysregulation in health and disease.

KEYWORDS:

Adrenergic receptor; Beta2-adrenergic receptor; Neuroimmune; Norepinephrine; Stress; Sympathetic nervous system

PMID:
24486056
PMCID:
PMC4116469
DOI:
10.1016/j.smim.2014.01.003
[Indexed for MEDLINE]
Free PMC Article

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