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Jpn J Cancer Res. 1987 Dec;78(12):1319-21.

Effects of a high-voltage electrical impulse and an anticancer drug on in vivo growing tumors.

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  • 1First Department of Surgery, Yamaguchi University School of Medicine.

Abstract

Application of a high-voltage electrical impulse (5 kV/cm, 2 msec) after bleomycin administration resulted in a significant size decrease of subcutaneously inoculated AH-109A hepatocellular carcinoma in Donryu rats. The tumor size decreased to an average of 17% of the initial mass 4 days after the treatment. Neither the high-voltage electrical impulse nor bleomycin administration alone showed an inhibitory effect on the tumor growth. It was concluded that the concomitant use of a high-voltage electrical impulse and an anticancer drug has the potential to be applicable for cancer treatment.

PMID:
2448275
[PubMed - indexed for MEDLINE]
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