Format

Send to

Choose Destination
Cell Res. 2014 Mar;24(3):263-4. doi: 10.1038/cr.2014.13. Epub 2014 Jan 31.

Where long noncoding RNAs meet DNA methylation.

Author information

1
Wistar Institute, Philadelphia, PA 19104, USA.

Abstract

DNA methylation is a fundamental epigenetic mechanism governing regulation of gene expression during mammalian development. A recent study published in Nature shows a novel long noncoding RNA (lncRNA) arising from the CEBPA gene locus (termed ecCEBPA) that is critical for regulation of DNA methylation at this site through the association of ecCEBPA with DNA methyltransferase 1, DNMT1.

PMID:
24481530
PMCID:
PMC3945889
DOI:
10.1038/cr.2014.13
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Nature Publishing Group Icon for PubMed Central
Loading ...
Support Center