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Nord J Psychiatry. 2014 Oct;68(7):507-12. doi: 10.3109/08039488.2013.877074. Epub 2014 Jan 29.

Prevalence of depression, quality of life and antidepressant treatment in the Danish General Suburban Population Study.

Author information

1
Christina Ellervik, M.D., Chief Physician, Department of Clinical Biochemistry, Naestved University Hospital, Copenhagen University Hospital , and Associate Professor, Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen , Denmark.

Abstract

BACKGROUND:

The Danish General Suburban Population Study (GESUS), the objective of which is to facilitate epidemiological and genetic research, has included the Major Depression Inventory (MDI) and the WHO-Five Well-Being Index (WHO-5) among the medical health questionnaires. We were thus in a position to compare the 2-week prevalence of ICD-10 depression in the period from 2010 to 2012 with our previous Danish general population study from 2003, in which the MDI was also included.

AIMS:

The aim of our analysis was not only to evaluate the point prevalence of ICD-10 depression but also to describe the prevalence of antidepressants received by the respondents in the GESUS study and the correspondence to their subjective well-being on the WHO-5 questionnaire.

METHODS:

To evaluate the validity (scalability) of the MDI and the WHO-5 in the GESUS study we performed the non-parametric Mokken analysis. The scalability of the MDI and the WHO-5 was quite acceptable.

RESULTS:

In total, 14,787 respondents were available from a response rate of 50%. The 2-week prevalence of ICD-10 depression was 2.3%, which is rather similar to the 2.8% in our 2003 study. The rate of people receiving antidepressants increased consistently with increasing severity of ICD-10 depression.

CONCLUSION:

This study has confirmed that the use of the MDI to obtain an ICD-10 depression diagnosis gives rather conservative estimates of the 2-week prevalence of depression in the Danish general population. The prescription of antidepressants depends on the severity of the ICD-10 depression diagnosis.

KEYWORDS:

Depressive illness; Major Depression Inventory; WHO-5

PMID:
24476587
DOI:
10.3109/08039488.2013.877074
[Indexed for MEDLINE]

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