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Mol Biol Rep. 2014;41(4):2559-69. doi: 10.1007/s11033-014-3114-9. Epub 2014 Jan 29.

X-chromosome STR markers data in a Cabo Verde immigrant population of Lisboa.

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Serviço de Genética e Biologia Forenses, Instituto Nacional de Medicina Legal e Ciências Forenses I.P., Delegação do Sul, Rua Manuel Bento de Sousa, no. 3, 1169-201, Lisboa, Portugal,


Population genetic data of 12 X chromosomal short tandem repeats markers (DXS10074, DXS10079, DXS10101, DXS10103, DXS10134, DXS10135, DXS10146, DXS10148, DXS7132, DXS7423, DXS8378 and HPRTB) were analysed in 54 females and 95 males of an immigrant population from Cabo Verde living in Lisboa. The obtained results for forensic statistical parameters such as observed heterozigosity, polymorphism information content, power of discrimination and mean exclusion chance, based on single allele frequencies, reveal that this multiplex system is highly informative and can represent an important tool for genetic identification purposes in the immigrant population of Cabo Verde. Since the studied short tandem repeats genetic markers are distributed on four linkage groups, that can provide independent genotype information, we studied those groups as haploytes. The forensic efficiency parameters for the linked groups were all higher than 0.97, with linkage group I being the most polymorphic and linkage group III the less informative.

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