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Laryngoscope. 2014 Jul;124(7):1668-73. doi: 10.1002/lary.24556. Epub 2014 Jan 28.

Glucocorticoids in laryngology: a review.

Author information

1
NYU Voice Center, Department of Otolaryngology-Head and Neck Surgery, New York University School of Medicine, New York, New York.

Abstract

OBJECTIVES/HYPOTHESIS:

To provide the otolaryngologist an evidence-based sound review of glucocorticoid use for laryngeal pathology.

STUDY DESIGN:

Review of contemporary peer-reviewed literature as well as review articles.

METHODS:

A review of the literature regarding glucocorticoids as a therapeutic intervention for the treatment of benign laryngeal pathology and laryngeal manifestations of systemic disease was performed. Review included both systemic administration as well as local injection.

RESULTS:

Glucocorticoids, administered in the critical care setting for planned extubation, markedly reducing the risk of reintubation and remain a rudimentary pharmacologic adjunct in laryngeal manifestations of common autoimmune and inflammatory disorders. Intralesional injection has reduced the rate of surgical intervention for benign inflammatory primary laryngeal pathology.

CONCLUSIONS:

Glucocorticoids are effective in the treatment of a number of laryngeal pathologies, through both systemic and intralesional administration. However, a clear consensus for utilization of glucocorticoids in the treatment of specific laryngeal disorders has yet to be published.

KEYWORDS:

Steroids; glucocorticoids; vocal folds; voice

PMID:
24474440
DOI:
10.1002/lary.24556
[Indexed for MEDLINE]

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