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Rev Bras Parasitol Vet. 2013 Oct-Dec;22(4):470-4. doi: 10.1590/S1984-29612013000400005.

Hematological values associated to the serological and molecular diagnostic in cats suspected of Ehrlichia canis infection.

Author information

1
Programa de Pós-graduação em Ciências Veterinárias, Faculdade de Agronomia, Medicina Veterinária e Zootecnia, Universidade Federal de Mato Grosso - UFMT, CuiabáMT, Brasil, Programa de Pós-graduação em Ciências Veterinárias, Faculdade de Agronomia, Medicina Veterinária e Zootecnia, Universidade Federal de Mato Grosso - UFMT, Cuiabá, MT, Brasil.
2
Laboratório de Virologia e Rickettsioses, Hospital Veterinário, Universidade Federal de Mato Grosso - UFMT, CuiabáMT, Brasil, Laboratório de Virologia e Rickettsioses, Hospital Veterinário, Universidade Federal de Mato Grosso - UFMT, Cuiabá, MT, Brasil.
3
Laboratório de Patologia Clínica Veterinária, Hospital Veterinário, Universidade Federal de Mato Grosso - UFMT, CuiabáMT, Brasil, Laboratório de Patologia Clínica Veterinária, Hospital Veterinário, Universidade Federal de Mato Grosso - UFMT, Cuiabá, MT, Brasil.

Abstract

The literature contains several studies on feline ehrlichiosis. However, information about the characteristics of Ehrlichia infection in cats is still scanty. This study evaluated the association between Ehrlichia spp. infection and the hematologic data of 93 cats treated at the Federal University of Mato Grosso Veterinary Hospital in Cuiabá, state of Mato Grosso, Brazil. The presence of or exposure to Ehrlichia spp. infection was evaluated by Polymerase Chain Reaction (PCR) targeting the dsb and 16S rRNA gene of Ehrlichia, and by detection of anti-Ehrlichia canis IgG antibodies in Indirect Fluorescence Assay (IFA), respectively. Eight (8.6%) cats tested positive by PCR and the partial DNA sequence obtained from PCR products was a 100% match to E. canis. Forty-two (45.1%) cats showed antibody reactivity against Ehrlichia spp. Hematological alterations such as low erythrocyte count, thrombocytopenia, lymphopenia and monocytosis were observed in PCR positive cats. Among them, low erythrocyte counts were associated with IgG antibody titers of 40 to 640 and five cats also tested positive by PCR. Furthermore, PCR-positive cats showed a tendency to be lymphopenic. No correlation was found between age and sex, and no ticks were observed in any of the examined cats.

PMID:
24473870
DOI:
10.1590/S1984-29612013000400005
[Indexed for MEDLINE]
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