Format

Send to

Choose Destination
Mol Microbiol. 2014 Mar;91(5):858-61. doi: 10.1111/mmi.12532. Epub 2014 Feb 18.

Helicobacter pylori: expect the unexpected.

Author information

1
Division of Gastroenterology, Departments of Medicine and Cancer Biology, Vanderbilt University, Nashville, TN, 37232, USA.

Abstract

Helicobacter pylori is one of the most common bacterial infections worldwide, and virtually all infected persons develop coexisting gastritis, a signature feature of which is the capacity to persist for decades. In support of its lifestyle, H. pylori has evolved to express an array of diverse phenotypes, including enzyme functional diversity, that help to subvert obstacles presented by the human host, which permits long-term microbial colonization. The versatility of the newly discovered enzyme LpxJ may allow H. pylori to quickly adapt to dynamic and hostile conditions present within its cognate gastric niche.

PMID:
24471732
PMCID:
PMC3966957
DOI:
10.1111/mmi.12532
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Wiley Icon for PubMed Central
Loading ...
Support Center