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PLoS One. 2014 Jan 22;9(1):e86200. doi: 10.1371/journal.pone.0086200. eCollection 2014.

HIV pre-exposure prophylaxis interest among female sex workers in Guangxi, China.

Author information

1
Guangxi Key Laboratory of AIDS Prevention and Treatment, School of Public Health, Guangxi Medical University, Nanning, Guangxi, China.
2
The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, Guangxi, China.
3
Guangxi Key Laboratory of AIDS Prevention and Treatment, School of Public Health, Guangxi Medical University, Nanning, Guangxi, China ; Department of Medicine, Boston Medical Center, Boston University School of Medicine, Boston, Massachusetts, United Staes of America.
4
School of Public Health, Chongqing Medical University, Chongqing, China.
5
State Key Laboratory for Infectious Disease Prevention and Control, Chinese Center for Disease Control and Prevention, Beijing, China.
6
Nanning Center for Disease Control and Prevention, Nanning, Guangxi, China.
7
Liuzhou Center for Disease Control and Prevention, Liuzhou, Guangxi, China.
8
Beihai Center for Disease Control and Prevention, Beihai, Guangxi, China.

Abstract

OBJECTIVES:

Acceptability of pre-exposure prophylaxis (PrEP) and willingness to participate in a clinical trial for both safety and efficacy of PrEP were investigated among female sex workers (FSWs) in Guangxi, China.

METHODS:

A cross-sectional study was performed in three cities in Guangxi. Structured, self-administered questionnaires were used to assess the acceptability of PrEP and the willingness to participate in a clinical trial. Multivariable logistic regression models were fitted to identify predictors.

RESULTS:

Among 405 participants, 15.1% had heard of PrEP. If PrEP was deemed to be effective, safe and provided for free, 85.9% reported that they would accept it, and 54.3% of those who accepted PrEP said that they would participate in a clinical trial. The increased acceptability of PrEP was associated with working in male dominated venues, higher income, a poor family relationship, better HIV/AIDS knowledge, not realizing HIV risk from unfamiliar clients, not being forced to use condoms by the gatekeepers, consistent use of condoms, and use of drugs to prevent STD infection. The increased willingness to participate in a clinical trial was associated with a poor family relationship, better HIV/AIDS knowledge, not realizing HIV risk from unfamiliar clients, a willingness to adhere to daily PreP use, and not being concerned about discrimination by others. The main reason for rejecting PrEP or participating in a clinical trial was the concern about the side effects of PrEP.

CONCLUSIONS:

Acceptability of PrEP among Guangxi FSWs is relatively high, indicating that PrEP intervention programs may be feasible for Chinese FSWs. Given the fact that most of the participants had never heard of PrEP before, and that family, gatekeepers, and social discrimination could significantly affect its acceptability, a comprehensive mix of multiple interventions is necessary for the successful implementation of a PrEP program among this population in Guangxi.

PMID:
24465956
PMCID:
PMC3899205
DOI:
10.1371/journal.pone.0086200
[Indexed for MEDLINE]
Free PMC Article
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