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J Hepatobiliary Pancreat Sci. 2014 Apr;21(4):246-50. doi: 10.1002/jhbp.83. Epub 2014 Jan 27.

Efficacy of 3D-positron emission tomography/computed tomography for upper abdomen.

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Division of Nuclear Medicine, Department of Diagnostic Radiology, School of Medicine, Keio University, 35 Shinanomachi, Shinjyuku-ku, Tokyo, 160-8582, Japan.


Recent advancement in computed tomography (CT) enables us to obtain high spatial resolution image and made it possible to construct extensive high-definition three-dimensional (3D) images. But a lack of contrast resolution in CT alone is still remained problem. Meanwhile, as fluorodeoxyglucose-positron emission tomography (PET) can visualize tumors in high contrast, we can create 3D images fusing the accumulation in tumors on PET/CT images. Such images can play the role of a "map of body" which makes it easy to understand the anatomical information before surgery. We also try to evaluate segmental liver function by using PET/CT fusion images. By using (11) C-methionine PET/contrast-enhanced CT, superior image quality compared to single photon emission computed tomography/CT can be obtained. CT, especially with contrast enhancement for obtaining anatomical imaging information plus PET for obtaining functional imaging information is a highly compatible combination, and adding these two types information will further increase clinical usefulness.


11C-methionine; 3D reconstruction; Computed tomography angiography; Fusion image; Hepatic function; Positron emission tomography/computed tomography

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