Is there a correlation between coronary artery ectasia and neutrophil-lymphocyte ratio?

Clin Appl Thromb Hemost. 2015 Apr;21(3):229-34. doi: 10.1177/1076029613520488. Epub 2014 Jan 24.

Abstract

We aimed to investigate the association between the neutrophil-lymphocyte ratio (NLR) and coronary artery ectasia (CAE). The study included 198 patients who had undergone coronary angiography for suspected coronary artery disease (CAD). The patients were divided into the following 4 groups: group 1, 44 patients with normal coronary arteries; group 2, 61 patients with CAD; group 3, 40 patients with isolated CAE; and group 4, 53 patients with CAE coexisting with CAD. Neutrophil-lymphocyte ratio was significantly lower in group 1 than the other groups and significantly higher in group 4. Patients in group 1 had significantly lower neutrophil counts and significantly higher lymphocyte counts than the patients in group 4. The isolated CAE and CAD groups were similar in terms of NLR, neutrophil count, and lymphocyte count. In addition, we found significant positive correlations between presence of ectasia, number of ectatic vessels, and NLR. Our findings provide additional evidence for the role of NLR in CAE.

Keywords: atherosclerosis; coronary artery ectasia; inflammation; neutrophil–lymphocyte ratio; white blood cells.

Publication types

  • Clinical Trial

MeSH terms

  • Aged
  • Coronary Angiography*
  • Coronary Artery Disease / blood*
  • Coronary Artery Disease / diagnostic imaging*
  • Coronary Vessels / diagnostic imaging*
  • Dilatation, Pathologic / blood
  • Dilatation, Pathologic / diagnostic imaging
  • Female
  • Humans
  • Lymphocyte Count
  • Lymphocytes
  • Male
  • Middle Aged
  • Neutrophils