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Am J Surg. 2014 Sep;208(3):480-4; discussion 483-4. doi: 10.1016/j.amjsurg.2013.09.020. Epub 2013 Dec 25.

Single institutional experience using biological mesh for abdominal wall reconstruction.

Author information

1
Department of Surgery, William Beaumont Hospital System, Oakland University, Royal Oak, MI, USA. Electronic address: anthony.iacco@beaumont.edu.
2
Department of Surgery, William Beaumont Hospital System, Oakland University, Royal Oak, MI, USA.

Abstract

BACKGROUND:

Complex ventral hernias remain a challenge. We present a study evaluating outcomes of complex ventral hernia repair using human-derived acellular dermal matrix (AlloDerm) and porcine-derived acellular dermal sheet (Permacol).

METHODS:

A retrospective review of 251 patients undergoing complex hernia repair was performed. Primary outcome was hernia recurrence; and secondary outcomes included early and late complications and mortality.

RESULTS:

Recurrence for Permacol versus AlloDerm was 32% versus 47% (P = .02). There was a difference in early complications (48% vs 30%, P = .007) and also late complications (30% vs 21%, P = .16) of Permacol versus AlloDerm. Overall survival was 85% for the Permacol group versus 78% for the AlloDerm group (P = .23). Recurrence for Permacol versus AlloDerm for underlay technique was 19% versus 22% and that for bridging technique was 44% versus 57%.

CONCLUSION:

There exists a high complication rate from both Permacol and AlloDerm in complex ventral hernia repair especially when used as a fascial bridge.

KEYWORDS:

Abdominal wall; Biologic; Hernia; Mesh; Ventral hernia

PMID:
24462172
DOI:
10.1016/j.amjsurg.2013.09.020
[Indexed for MEDLINE]

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