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Clin Imaging. 2014 May-Jun;38(3):367-71. doi: 10.1016/j.clinimag.2013.12.005. Epub 2013 Dec 21.

Pineal gland involvement in Erdheim-Chester disease detected on (18)F-FDG PET-CT imaging: a case report and review of literature.

Author information

1
Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.
2
Department of Pathology, All India Institute of Medical Sciences, New Delhi, India.
3
Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India. Electronic address: rkphulia@yahoo.com.

Abstract

Erdheim-Chester disease (ECD) is a rare non-Langerhan's cell histiocytosis affecting multiple organ systems. The most common systemic manifestations are bone lesions, infiltration of the pituitary stalk sometimes leading to diabetes insipidus, pulmonary fibrosis, cardiac failure and exophthalmus. Neurological symptoms as the first clinical manifestations of ECD have been reported in less than one third of cases. We report a rare presentation of a patient of ECD on 18F-fluorodeoxyglucose ((18)F-FDG) positron emission tomography-computed tomography which revealed abnormal (18)F-FDG accumulation in the region of pineal gland, pericardium and bilateral distal tibiae.

KEYWORDS:

(18)F-FDG; Erdheim-Chester disease (ECD); PET-CT; Pineal gland

PMID:
24461468
DOI:
10.1016/j.clinimag.2013.12.005
[Indexed for MEDLINE]

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