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Clin Nucl Med. 2014 Mar;39(3):274-6. doi: 10.1097/RLU.0000000000000333.

Diffuse renal parenchyma uptake with bone scintigraphy in a patient with paroxysmal nocturnal hemoglobinuria and normal kidney function.

Author information

1
From the Departments of *Nuclear Medicine, †Hematology, and ‡Nephrology, Medical Center Leeuwarden, Leeuwarden, the Netherlands.

Abstract

A 41-year-old woman with a Harrington spondylodesis presented with lower back pain. Bone scintigraphy showed diffusely increased parenchymal uptake in both kidneys. She reported 2 previous periods of dark, almost black, urine. Additional flow cytometric analysis confirmed the diagnosis of paroxysmal nocturnal hemoglobinuria. The increased renal parenchyma uptake is very probably due to paroxysmal nocturnal hemoglobinuria-related renal hemosiderosis. Remarkably, the patient did not develop any abnormality of renal function.

PMID:
24458177
DOI:
10.1097/RLU.0000000000000333
[Indexed for MEDLINE]

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