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Rev Esp Geriatr Gerontol. 2014 May-Jun;49(3):129-36. doi: 10.1016/j.regg.2013.08.002. Epub 2014 Jan 21.

[Use of methadone in the elderly with cancer pain: a systematic review].

[Article in Spanish]

Author information

1
Servicio de Oncología Médica, Institut Català d́Oncologia, Hospital Duràn i Reynals, L'Hospitalet de Llobregat, Barcelona, España.
2
Servicio de Cuidados Paliativos, Institut Català d́Oncologia, Hospital Duràn i Reynals, L'Hospitalet de Llobregat, Barcelona, España; Grup de Cures Pal·liatives, Institut d'Investigació Biomèdica de Bellvitge (IDIBELL), L'Hospitalet de Llobregat, Barcelona, España; Facultat de Medicina, Universitat Internacional de Catalunya, Barcelona, España.
3
Servicio de Cuidados Paliativos, Institut Català d́Oncologia, Hospital Duràn i Reynals, L'Hospitalet de Llobregat, Barcelona, España; Grup de Cures Pal·liatives, Institut d'Investigació Biomèdica de Bellvitge (IDIBELL), L'Hospitalet de Llobregat, Barcelona, España; Càtedra de Cures Pal·liatives-Centre d'Estudis Sanitaris i Socials, Universitat de Vic, Vic, España; Comisión de Oncogeriatría, Institut Català d́Oncologia, Hospital Duràn i Reynals, L'Hospitalet de Llobregat, Barcelona, España. Electronic address: jgonzalez@iconcologia.net.

Abstract

OBJECTIVE:

To identify the clinical use of methadone as an analgesic in the management of cancer pain in elderly patients.

MATERIAL AND METHODS:

We performed a systemic review of the literature on the specific use of methadone in elderly with cancer pain in MEDLINE, COCHRANE DATABASE and SCOPUS. A second search was conducted in MEDLINE to look for clinical trials and systematic review of the use of methadone in cancer pain, selecting only those in which the mean age of patients was ≥ 65 years old.

RESULTS:

Four articles were obtained in the first search, and from the second 7 clinical trials, none of them specific to methadone use in elderly patients with cancer.

CONCLUSIONS:

There are insufficient data on the use of methadone as an analgesic in the elderly with cancer. Given its pharmacological characteristics it must be used by trained personnel. Several recommendations are proposed for its use as an analgesic in the treatment of cancer pain in the elderly.

KEYWORDS:

Aged; Anciano; Dolor; Metadona; Methadone; Neoplasia; Neoplasms; Pain

PMID:
24457178
DOI:
10.1016/j.regg.2013.08.002
[Indexed for MEDLINE]

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