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ScientificWorldJournal. 2013 Dec 25;2013:785929. doi: 10.1155/2013/785929. eCollection 2013.

Diagnostic concordance characteristics of oral cavity lesions.

Author information

  • 1Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Çukurova University, Saricam-Balcali, 01330 Adana, Turkey.
  • 2Department of Pathology, Faculty of Medicine, Çukurova University, 01330 Adana, Turkey.
  • 3Private Practice in Oral and Maxillofacial Surgery, 01120 Adana, Turkey.
  • 4Department of Biostatistics, Faculty of Medicine, Çukurova University, 01330 Adana, Turkey.
  • 5Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Mustafa Kemal University, 31100 Hatay, Turkey.



The objective of this study was to evaluate the diagnostic concordance characteristics of oral cavity lesions by comparing the clinical diagnosis of the lesions with the histopathologic diagnosis.


A retrospective analysis was conducted on the patients, who were admitted with oral cavity pathology and underwent biopsy procedure between 2007 and 2011. The oral cavity lesions were classified into 6 different groups as odontogenic cysts, nonodontogenic cysts, odontogenic tumors, nonodontogenic tumors, malignant tumors, and precancerous lesions in accordance with the 2005 WHO classification. The diagnoses were also recategorized into 3 groups expressing prognostic implications as benign, precancerous, and malignant. The initial clinical diagnoses were compared with the histopathologic diagnoses. Data were analyzed statistically.


A total of 2718 cases were included. Histopathologic diagnosis did not match the clinical diagnosis in 6.7% of the cases. Nonodontogenic tumors and malignant tumors had the highest misdiagnosis rates (11.5% and 9%, resp.), followed by odontogenic tumors (7.7%), precancerous lesions (6.9%), and odontogenic cysts (4.4%). Clinicians were excelled in diagnosis of benign and precancerous lesions in clinical setting.


The detailed discordance characteristics for each specific lesion should be considered during oral pathology practice to provide early detection without delay.

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