Specific effects of sedative/hypnotic drugs in the treatment of incapacitating chronic insomnia

Am J Med. 1987 Nov;83(5):909-16. doi: 10.1016/0002-9343(87)90650-4.

Abstract

Sedative/hypnotic drugs for the treatment of chronic insomnia are generally considered ineffective by most experts but helpful by many patients. Occasionally, insomnia-induced debilitations may be remedied by long-term use of sedative/hypnotic drugs; some examples are given. The present discrepancy between expert and patient opinion may be derived from current research practices. The improbability that series of sedative/hypnotic drug trials will be carried out for patients with insomnia further biases against observation of rarer but clinically significant distinctions among these drugs.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Aged
  • Diazepam / therapeutic use
  • Female
  • Humans
  • Hydromorphone / therapeutic use
  • Hypnotics and Sedatives / therapeutic use*
  • Male
  • Methaqualone / therapeutic use
  • Phenobarbital / therapeutic use
  • Sleep Initiation and Maintenance Disorders / drug therapy*
  • Sleep Initiation and Maintenance Disorders / psychology

Substances

  • Hypnotics and Sedatives
  • Methaqualone
  • Diazepam
  • Hydromorphone
  • Phenobarbital