Format

Send to

Choose Destination
Am Soc Clin Oncol Educ Book. 2012:576-84. doi: 10.14694/EdBook_AM.2012.32.576.

Identification, management, and evaluation of children with cancer-predisposition syndromes.

Author information

1
From the Cincinnati Children's Hospital Medical Center, Cincinnati, OH; Children's Hospital of Philadelphia, Philadelphia, PA; Huntsman Cancer Institute, Salt Lake City, UT; Center for Children's Cancer Research (C3R), Huntsman Cancer Institute, Salt Lake City, UT.

Abstract

A substantial proportion of childhood cancers are attributable to an underlying genetic syndrome or inherited susceptibility. Recognition of affected children allows for appropriate cancer risk assessment, genetic counseling, and testing. Identification of individuals who are at increased risk to develop cancers during childhood can guide cancer surveillance and clinical management, which may improve outcomes for both the patient and other at-risk relatives. The information provided through this article will focus on the current complexities involved in the evaluation and management of children with cancer-predisposing genetic conditions and highlight remaining questions for discussion.

Supplemental Content

Loading ...
Support Center