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Comp Immunol Microbiol Infect Dis. 2014 Mar;37(2):97-108. doi: 10.1016/j.cimid.2013.10.001. Epub 2013 Oct 14.

Antibiotic susceptibility of bacteria isolated from infections in cats and dogs throughout Europe (2002-2009).

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Vétoquinol S.A., Centre de recherche, 34 rue du Chêne Sainte Anne, 70200 Lure, France.
Vétoquinol S.A., 31 rue des Jeûneurs, 75002 Paris, France.
Université ParisEst, UMR 956 Anses/ENVA USC INRA, Microbiologie, École Nationale Vétérinaire d'Alfort, 7 avenue du Général de Gaulle, 94700 Maisons-Alfort, France. Electronic address:


A monitoring program of the pre-treatment susceptibility of clinical isolates of bacteria from diseased dogs and cats was active between the years 2002 and 2009. Susceptibility of each isolated strain to a panel of nine antibiotics (amoxicillin/clavulanic acid, ampicillin, penicillin, clindamycin, doxycycline, enrofloxacin, marbofloxacin, trimethoprim and trimethoprim/sulfamethoxazole) was assessed. The Minimum Inhibitory Concentration (MIC) of marbofloxacin was also determined by a standardized microdilution technique following CLSI recommendations. In total, 1857 bacterial strains were collected throughout Europe from cases of otitis, respiratory, urinary and dermatological infections. Although bacterial susceptibility varied for each of the antibiotics within the panel, patterns of susceptibility were similar to those described in the literature for comparable time periods and geographical areas. With a clinical resistance varying from 0 to 14.48% against the isolated strains, marbofloxacin susceptibility was very high and remains an effective antibiotic for the treatment of otitis, urinary, respiratory and dermatological infections in companion animals.


Antimicrobial susceptibility; Cats; Dermatological infection; Dogs; Fluoroquinolone; Marbofloxacin; Otitis; Respiratory; Survey; Urinary

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