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Hum Pathol. 2014 Mar;45(3):648-52. doi: 10.1016/j.humpath.2013.09.015. Epub 2013 Oct 8.

Primary anorectal Hodgkin lymphoma: report of a case and review of the literature.

Author information

1
Department of Medical Biotechnology, Section of Pathology, University of Siena, 53100, Siena, Italy. Electronic address: maradot@libero.it.
2
Department of Medical Biotechnology, Section of Pathology, University of Siena, 53100, Siena, Italy.
3
Surgery Unit Valdichiana Hospital, Montepulciano, 53045, Montepulciano, Italy.
4
Section of Pathology, Azienda Ospedaliera Universitaria Senese, 53100, Siena, Italy.

Abstract

Primary colorectal lymphomas are very rare. They are mostly B-cell non-Hodgkin lymphomas. Only 2 cases of anorectal Hodgkin lymphoma have been described so far, both affecting HIV-infected males and showing Epstein-Barr virus infection. We report an unusual case of primary Hodgkin lymphoma of the anorectal region in an HIV-negative, Epstein-Barr virus-infected patient and in the absence of inflammatory bowel disease. The importance of distinguishing Hodgkin lymphoma from Epstein-Barr virus-induced lymphoproliferative disorders and from Epstein-Barr virus-positive diffuse large B-cell lymphoma of the elderly is stressed in particular in non-immunocompromised patients and in the absence of history of inflammatory bowel disease.

KEYWORDS:

Anorectal lymphoma; EBV; Hodgkin lymphoma; Immunosuppression; Large bowel tumors

PMID:
24440095
DOI:
10.1016/j.humpath.2013.09.015
[Indexed for MEDLINE]

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