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Cell Host Microbe. 2014 Jan 15;15(1):1-2. doi: 10.1016/j.chom.2013.12.005.

Mycobacterial lipid logic.

Author information

1
Department of Chemistry, University of California, Berkeley, Berkeley, CA 94720, USA.
2
Department of Chemistry, University of California, Berkeley, Berkeley, CA 94720, USA; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA; Howard Hughes Medical Institute, University of California, Berkeley, Berkeley, CA 94720, USA. Electronic address: crb@berkeley.edu.

Abstract

During infection of the lung epithelium, Mycobacterium tuberculosis must infect and survive within macrophages long enough to be transported into deeper lung tissues. Cambier et al. (2013) show that pathogenic mycobacteria use the coordinated action of two cell wall glycolipids to regulate macrophage recruitment to initial infection sites.

PMID:
24439891
PMCID:
PMC4123792
DOI:
10.1016/j.chom.2013.12.005
[Indexed for MEDLINE]
Free PMC Article

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