Format

Send to

Choose Destination
Blood. 2014 Jan 16;123(3):307-8. doi: 10.1182/blood-2013-11-538298.

Neutrophil survival in the death zone.

Author information

1
BOSTON CHILDREN'S HOSPITAL.

Abstract

In this issue of Blood, Thompson et al reveal a key role for hypoxia-inducible factor (HIF)-2a in the adaptation of neutrophils to hypoxia. Tissue hypoxia is a common feature of trauma and inflammation. Infiltrating neutrophils must adapt to this low-oxygen environment to satisfy the metabolic and functional demands of an immune response.

PMID:
24434994
DOI:
10.1182/blood-2013-11-538298
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Silverchair Information Systems
Loading ...
Support Center