Approaches to the treatment of disease induced by chikungunya virus

Indian J Med Res. 2013 Nov;138(5):762-5.

Abstract

Chikungunya virus, a re-emerging mosquito-borne alphavirus, causes fever, rash and persistent arthralgia/arthritis in humans. Severe outbreaks have occurred resulting in infections of millions of people in Southeast Asia and Africa. Currently there are no antiviral drugs or vaccines for prevention and treatment of chikungunya infections. Herein we report the current status of research on antiviral drugs and vaccines for chikungunya virus infections.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Aedes / virology
  • Africa / epidemiology
  • Alphavirus Infections / drug therapy*
  • Alphavirus Infections / epidemiology
  • Alphavirus Infections / immunology
  • Alphavirus Infections / transmission
  • Animals
  • Antiviral Agents / therapeutic use*
  • Asia, Southeastern
  • Chikungunya Fever
  • Chikungunya virus / immunology*
  • Chikungunya virus / pathogenicity
  • Disease Outbreaks
  • Fever / drug therapy
  • Fever / epidemiology
  • Fever / virology
  • Humans
  • Insect Vectors
  • Vaccines / therapeutic use*

Substances

  • Antiviral Agents
  • Vaccines