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Med Mycol Case Rep. 2013 Jun 20;2:132-3. doi: 10.1016/j.mmcr.2013.06.002. eCollection 2013.

Cutaneous protothecosis in a patient with hypogammaglobulinemia.

Author information

  • 1Austin Centre for Infection Research, Austin Health, Heidelberg, VIC 3084, Australia ; Department of Microbiology, Austin Health, Heidelberg, VIC 3084, Australia.
  • 2Department of Microbiology, Austin Health, Heidelberg, VIC 3084, Australia.
  • 3Austin Centre for Infection Research, Austin Health, Heidelberg, VIC 3084, Australia.

Abstract

Prototheca wickerhamii has been predominantly recognised as a pathogen in immunocompromised hosts with deficits in innate or cellular immunity. The role of specific immunoglobulin against Prototheca in host immunity is uncertain. We describe a case of persistent cutaneous protothecosis in a patient with hypogammaglobulinemia most likely due to common variable immunodeficiency, with clinical response to voriconazole.

KEYWORDS:

Common variable immunodeficiency; Hypogammaglobulinemia; Prototheca; Protothecosis; Voriconazole

PMID:
24432237
PMCID:
PMC3885952
DOI:
10.1016/j.mmcr.2013.06.002
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