Format

Send to

Choose Destination
See comment in PubMed Commons below
Autoimmun Rev. 2014 Apr-May;13(4-5):408-11. doi: 10.1016/j.autrev.2014.01.025. Epub 2014 Jan 11.

Diagnosis and classification of Addison's disease (autoimmune adrenalitis).

Author information

1
Emergency Division, Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
2
Rheumatology Division, Aliança Medical Center, Salvador, Bahia, Brazil. Electronic address: rodneto@gmail.com.

Abstract

Autoimmune adrenalitis, or autoimmune Addison disease (AAD), is the most prevalent cause of primary adrenal insufficiency in the developed world. AAD is rare and can easily be misdiagnosed as other conditions. The diagnosis depends on demonstrating inappropriately low cortisol production and the presence of high titers of adrenal cortex autoantibodies (ACAs), along with excluding other causes of adrenal failure using other tests as necessary. The treatment corticosteroid replacement, and the prognosis following the treatment is the same as the normal population. Spontaneous recovery of adrenal function has been described but is rare.

PMID:
24424183
DOI:
10.1016/j.autrev.2014.01.025
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center