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Int Rev Immunol. 2014 Jan;33(1):1-2. doi: 10.3109/08830185.2014.877705.

In this issue: autoimmunity and innate immunity.

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1
Editor-in-Chief, International Reviews of Immunology, Vice President, Scientific Affairs, Kite Pharma, Inc., Santa Monica, CA, USA.

Abstract

In this issue of the journal, we host a range of topics relevant to innate immunity as well as certain inflammatory diseases. More specifically, Sanz et al. cover a tantalizing form of death called pyroptosis that leads to inflammation. Samasca et al. provide a brief perspective on celiac disease. Singh and collaborators discuss in detail a newly designed leptin antagonist that could be applicable to colitis treatment. Through a meta-analysis, Wen et al. show that IL-18 gene polymorphism is associated with RA and SLE. Adenovirus-triggered innate immunity is discussed by Chen and Lee. Further, Zheng et al. provide a review of lectin receptors and their importance to anti-microbial immunity. Finally, Rojas et al. discuss tantalizing evidence supporting the fact that endogenous danger motifs such as advanced glycation end products are recognized via a TLR-like molecule and signaling pathway.

PMID:
24423193
DOI:
10.3109/08830185.2014.877705
[Indexed for MEDLINE]
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