Hear the beat: decellularized mouse heart regenerated with human induced pluripotent stem cells

Expert Rev Cardiovasc Ther. 2014 Feb;12(2):135-7. doi: 10.1586/14779072.2014.879039. Epub 2014 Jan 13.

Abstract

Heart tissue engineering holds a great potential for human heart disease therapy. Regeneration of whole biofunctional human heart is the ultimate goal of tissue engineering. Recent advances take the first step towards whole heart regeneration. However, a substantial amount of challenges have to be overcome.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Heart / physiology
  • Heart / physiopathology
  • Heart Diseases / therapy*
  • Humans
  • Induced Pluripotent Stem Cells / transplantation*
  • Mice
  • Regeneration
  • Tissue Engineering / methods*