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Vaccine. 2014 Feb 12;32(8):897-900. doi: 10.1016/j.vaccine.2013.12.065. Epub 2014 Jan 9.

Decline of varicella vaccination in German surveillance regions after recommendation of separate first-dose vaccination for varicella and measles-mumps-rubella.

Author information

1
Department of Paediatrics, University of Würzburg, Josef-Schneider-Str. 2, 97080 Würzburg, Germany. Electronic address: Streng_A@ukw.de.
2
Department of Paediatrics, University of Würzburg, Josef-Schneider-Str. 2, 97080 Würzburg, Germany.

Abstract

BACKGROUND:

Germany introduced routine varicella (V) vaccination in 2004. Due to a slightly increased risk of febrile convulsions after first-dose application of combined measles-mumps-rubella-varicella (MMRV) vaccine separate first-dose vaccinations with MMR and monovalent V vaccine were recommended in September 2011.

METHODS:

We compared V and MMR vaccinations in paediatric practices from two surveillance regions (Munich and Würzburg) one year before and after the change in the recommendation.

RESULTS:

A total of 1405/326 monthly reports were provided by a monthly average of 79/14 practices participating in Munich/Würzburg. V first-dose vaccinations (monovalent V or MMRV vaccine) declined by 12% in Munich (from 10.1 to 8.9 vaccinations per month and practice; p<0.005) and by 4% in Würzburg (from 9.9 to 9.5; p=0.620), respectively. First-dose vaccinations for MMR (MMR or MMRV vaccine) did not change significantly in both regions.

CONCLUSION:

Acceptance of V vaccination depends in part on the use of combination vaccine.

KEYWORDS:

Surveillance; Vaccination; Varicella

PMID:
24412300
DOI:
10.1016/j.vaccine.2013.12.065
[Indexed for MEDLINE]

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