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Genome Announc. 2014 Jan 9;2(1). pii: e01146-13. doi: 10.1128/genomeA.01146-13.

Draft Genome Sequence of Streptomyces niveus NCIMB 11891, Producer of the Aminocoumarin Antibiotic Novobiocin.

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Pharmaceutical Institute, Tübingen University, Tübingen, Germany.


Streptomyces niveus NCIMB 11891 is the producer of the gyrase inhibitor novobiocin, which belongs to the aminocoumarin class of antibiotics. The genome sequence of this strain was found to contain, besides the gene cluster for novobiocin, a putative gene cluster for the macrolactam antibiotic BE-14106 and further secondary metabolite gene clusters.

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