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Eksp Onkol. 1987;9(3):43-8.

[Morphometric characteristics of argentaffin nucleolar structures in peripheral blood lymphoid cells from patients with non-Hodgkin's lymphomas and chronic lymphoid leukemias].

[Article in Russian]


Interphase lymphoid nucleoli of Ag-NOR stained site areas were measured on the TAS system in peripheral blood lymphoid cells with the known immunologic phenotype of 19 patients with lymphoid neoplasia (non-Hidgkin's lymphoma, CLL, hair-cell leukemia) and 10 healthy donors. The area of Ag-granules in neoplastic cells is much greater than in normal lymphocytes and does not correlate with a proliferation of cells but correlates with a malignancy grade of the disease. These data are discussed in terms of rDNA transcription patterns in malignant cells.

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