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Telemed J E Health. 2014 Mar;20(3):235-40. doi: 10.1089/tmj.2013.0162. Epub 2014 Jan 3.

Self-assessment tool of disease activity of rheumatoid arthritis by using a smartphone application.

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1
1 Department of Physical Therapy, Human Health Sciences, Kyoto University Graduate School of Medicine , Kyoto, Japan .

Abstract

OBJECTIVES:

The disease activities of rheumatoid arthritis (RA) tend to fluctuate between visits to doctors, and a self-assessment tool can help patients accommodate to their current status at home. The aim of the present study was to develop a novel modality to assess the disease activity of RA by a smartphone without the need to visit a doctor.

SUBJECTS AND METHODS:

This study included 65 patients with RA, 63.1 ± 11.9 years of age. The 28-joint disease activity score (DAS28) was measured for all participants at each clinic visit. The patients assessed their status with the modified Health Assessment Questionnaire (mHAQ), a self-assessed tender joint count (sTJC), and a self-assessed swollen joint count (sSJC) in a smartphone application. The patients' trunk acceleration while walking was also measured with a smartphone application. The peak frequency, autocorrelation (AC) peak, and coefficient of variance of the acceleration peak intervals were calculated as the gait parameters.

RESULTS:

Univariate analyses showed that the DAS28 was associated with mHAQ, sTJC, sSJC, and AC (p<0.05). In a stepwise linear regression analysis, mHAQ (β = 0.264, p<0.05), sTJC (β = 0.581, p<0.001), and AC (β = -0.157, p<0.05) were significantly associated with DAS28 in the final model, and the predictive model explained 67% of the DAS28 variance.

CONCLUSIONS:

The results suggest that noninvasive self-assessment of a combination of joint symptoms, limitations of daily activities, and walking ability can adequately predict disease activity of RA with a smartphone application.

PMID:
24404820
DOI:
10.1089/tmj.2013.0162
[Indexed for MEDLINE]
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