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J Clin Microbiol. 2014 Mar;52(3):994-7. doi: 10.1128/JCM.03044-13. Epub 2014 Jan 8.

Impact of new antifungal breakpoints on antifungal resistance in Candida species.

Author information

1
Fungus Testing Laboratory, Department of Pathology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.

Abstract

We reviewed our antifungal susceptibility data for micafungin, anidulafungin, fluconazole, and voriconazole against Candida species and compared resistance rates determined by the previous and recently revised CLSI antifungal breakpoints. With the new breakpoints, resistance was significantly increased for micafungin (from 0.8% to 7.6%), anidulafungin (from 0.9% to 7.3%), and voriconazole (from 6.1% to 18.4%) against Candida glabrata. Resistance was also increased for fluconazole against Candida albicans (from 2.1% to 5.7%).

PMID:
24403302
PMCID:
PMC3957792
DOI:
10.1128/JCM.03044-13
[Indexed for MEDLINE]
Free PMC Article

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