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Arch Ital Urol Androl. 2013 Dec 31;85(4):197-9. doi: 10.4081/aiua.2013.4.197.

Role of phytotherapy associated with antibiotic prophylaxis in female patients with recurrent urinary tract infections.

Author information

1
Clinica Urologica e Andrologica di Perugia, Università degli Studi di Perugia. emanuela.frumenzio@virgilio.it.

Abstract

OBJECTIVE:

Aim of this study is to evaluate the efficacy of a phytotherapic which includes Solidago, Orthosiphon and Birch extract (Cistimev®) in association with antibiotic prophylaxis in female patients affected by recurrent urinary tract infections (UTIr).

MATERIALS AND METHODS:

Patients affected by UTIr older than 18 years started a 3-months antibiotic prophylaxis (Prulifloxacin 600 mg, 1 cps/week or Phosphomicyn 1 cachet/week) according to antibiogram after urine culture. The patients were divided in 2 groups: Group A: antibiotic prophylaxis plus phytotherapy (1 cps/die for 3 months) and Group B: antibiotic prophylaxis alone.

RESULTS:

164 consecutive patients were studied: 107 were included in group A (mean age 59 ± 17.3 years) and 57 (mean age 61 ± 15.7) in group B. During the treatment period the relapse frequencies between the two groups were not significantly different (p = 0.854): 12/107 (11.21%) patients interrupted the treatment for UTIr in group A and 6/57 (10.52%) in group B. In the long term follow-up the relapse UTI risk was significant different in the two groups with a relapse risk 2.5 greater in group B than in group A (p < 0.0001).

CONCLUSION:

Our study demonstrated that in female patients affected by recurrent UTI, the association between antibiotic prophylaxis and of a phytotherapic which includes Solidago, Orthosiphon and Birch extract reduced the number of UTI in the 12 months following the end of prophylaxis and obtained a longer relapsing time, greatly improving the quality of life of the patients.

PMID:
24399121
DOI:
10.4081/aiua.2013.4.197
[Indexed for MEDLINE]
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