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Obstet Gynecol Sci. 2013 Nov;56(6):420-5. doi: 10.5468/ogs.2013.56.6.420. Epub 2013 Nov 15.

Small cell neuroendocrine carcinoma of the uterine cervix presenting with syndrome of inappropriate antidiuretic hormone secretion.

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  • 1Department of Obstetrics and Gynecology, The Catholic University of Korea College of Medicine, Seoul, Korea.


Small cell carcinoma of the uterine cervix is rare. It is estimated that 10% of patients with small-cell lung cancer have syndrome of inappropriate secretion of antidiuretic hormone (SIADH) and hyponatremia has been reported to be significantly associated with a poor prognosis. A proportion of small cell carcinoma of the uterine cervix exhibit neuroendocrine characteristics as revealed by immunohistochemistry, However, cases presenting typical symptoms due to SIADH are extremely rare. This report of the SIADH of the uterine cervix is a rare case in the small cell carcinoma of the cervix presenting with tumor-associated paraneoplastic syndrome.


Cervical cancer; Small cell carcinoma; Syndrome of inappropriate antidiuretic hormone secretion

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