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Gynecol Obstet Fertil. 2014 May;42(5):331-3. doi: 10.1016/j.gyobfe.2013.08.010. Epub 2014 Jan 3.

[Granulosa cell tumor of the ovary: retrospective study of 17 cases].

[Article in French]

Author information

1
Département de chirurgie oncologique, institut de cancérologie de Lorraine, université de Lorraine, 6, avenue de Bourgogne, CS 30519, 54519 Vandœuvre-lès-Nancy cedex, France. Electronic address: laureemilie.rebstock@gmail.com.
2
Département de chirurgie oncologique, institut de cancérologie de Lorraine, université de Lorraine, 6, avenue de Bourgogne, CS 30519, 54519 Vandœuvre-lès-Nancy cedex, France.
3
Service de biopathologie, unité d'anatomie pathologique, institut de cancérologie de Lorraine, université de Lorraine, 6, avenue de Bourgogne, CS 30519, 54519 Vandœuvre-lès-Nancy cedex, France.
4
Département de biostatistiques, institut de cancérologie de Lorraine, université de Lorraine, 6, avenue de Bourgogne, CS 30519, 54519 Vandœuvre-lès-Nancy cedex, France.
5
Département de chirurgie oncologique, institut de cancérologie de Lorraine, université de Lorraine, 6, avenue de Bourgogne, CS 30519, 54519 Vandœuvre-lès-Nancy cedex, France; Département de chirurgie oncologique, institut de cancérologie de Lorraine, CRAN, UMR 7039, université de Lorraine, CNRS, 6, avenue de Bourgogne, CS 30519, 54519 Vandœuvre-lès-Nancy cedex, France.

Abstract

Granulosa cell tumors of the ovary are rare tumor of ovary, included in the sex cord-stromal tumor category, hormone secreting. Seventeen patients with adult-type granulosa cell tumor were identified between 1995 and 2012. All have received surgical treatment first at stage I. Thirty-three percent of the patients relapsed with peritoneal nodules in 68% of the cases, treated surgically and sometimes with complementary therapies, such as chemotherapy, radiotherapy, hormonal treatment. Overall survival and recurrence-free survival were 100% and 58.3%, respectively at 10 years with median time to recurrence of 6 years (4-27). These tumors have therefore a good prognosis and require long-time follow-up. Finally, the prognostic factors of recurrence identified in the literature are FIGO stage, the presence of residual tumor and tumor size.

KEYWORDS:

Facteurs pronostiques; Granulosa cell tumors; Prognostic factors; Recurrence; Récidive; Tumeur de la Granulosa

PMID:
24394321
DOI:
10.1016/j.gyobfe.2013.08.010
[Indexed for MEDLINE]

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