The influence of sulfathiazole on the macroalgae Ulva lactuca

Chemosphere. 2014 Apr:100:105-10. doi: 10.1016/j.chemosphere.2013.12.038. Epub 2014 Jan 3.

Abstract

Sulfonamides (SA) are a class of antibiotics routinely found in environmental matrices and therefore their role as contaminants should be investigated in non-target organisms. With this purpose the present experimental work has evaluated the exposure of the chlorophycean Ulva lactuca L. to sulfathiazole (STZ), a SA drug commonly used in aquaculture, at two concentrations representing prophylactic (25 μg mL(-1)) and therapeutic (50 μg mL(-1)) administrations. Results showed that STZ exhibits high stability in seawater with only 18% degradation over the 5d assay at both dosages tested. Also, macroalgae demonstrated an efficient uptake capacity with constant internal concentrations after 24h regardless of the external solutions and thus should be considered as a bioindicator species in risk assessment. Both STZ concentrations induced a slight inhibition of the macroalgae growth after 96 h.

Keywords: Antibiotic; Bioindicators; Contamination; Macroalgae; Sulfathiazole; Ulva lactuca.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Drug Stability
  • Environmental Monitoring / methods*
  • Food Chain
  • Seawater / chemistry
  • Seaweed / drug effects
  • Seaweed / growth & development
  • Seaweed / metabolism
  • Sulfathiazole
  • Sulfathiazoles / metabolism
  • Sulfathiazoles / toxicity*
  • Ulva / drug effects*
  • Ulva / growth & development
  • Ulva / metabolism
  • Water Pollutants, Chemical / metabolism
  • Water Pollutants, Chemical / toxicity*

Substances

  • Sulfathiazoles
  • Water Pollutants, Chemical
  • Sulfathiazole