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J Pak Med Assoc. 2013 Oct;63(10):1312-5.

Glucagon-like peptide-1 receptors agonists (GLP1 RA).

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Department of Endocrinology, Bharti Hospital, Karnal, India.


The glucagon-like peptide-1 receptors agonists (GLP1RA) are a relatively new class of drugs, used for management of type 2 diabetes. This review studies the characteristics of these drugs, focusing upon their mechanism of action, intra-class differences, and utility in clinical practice. It compares them with other incretin based therapies, the dipeptidyl peptidase-IV inhibitors, and predicts future developments in the use of these molecules, while highlighting the robust indications for the use of these drugs.

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