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ISRN Psychiatry. 2013 Dec 10;2013:901987. doi: 10.1155/2013/901987. eCollection 2013.

No Association between Depression and Risk of Hepatocellular Carcinoma in Older People in Taiwan.

Author information

  • 1School of Medicine, China Medical University, Taichung 404, Taiwan ; Department of Family Medicine, China Medical University Hospital, Taichung 404, Taiwan.
  • 2Department of Public Health, China Medical University, Taichung 404, Taiwan ; Management Office for Health Data, China Medical University Hospital, Taichung 404, Taiwan.
  • 3Graduate Institute of Integrated Medicine, China Medical University, Taichung 404, Taiwan ; Department of Internal Medicine, Taichung Tzu Chi General Hospital, No. 66, Sec. 1, Fongsing Road, Tanzi District, Taichung 427, Taiwan.
  • 4Graduate Institute of Integrated Medicine, China Medical University, Taichung 404, Taiwan ; Department of Urology, China Medical University Hospital, Taichung 404, Taiwan.

Abstract

Objectives. The objective of this study was to determine whether there is a relationship between depression and risk of hepatocellular carcinoma (HCC) in older people in Taiwan. Methods. A case-control study was conducted to analyze the database from the Taiwan National Health Insurance program. We selected 1815 subjects aged 65 years or older with newly diagnosed HCC as the case group and 7260 subjects without HCC as the comparison group, from 2000 to 2010. Both groups were compared to measure the risk of HCC. Results. After controlling for confounders, the odds ratio of HCC was 0.81 in subjects with depression (95% confidence interval = 0.59, 1.11), as compared with nondepressed subjects. Conclusions. We conclude that no association is detected between depression and risk of hepatocellular carcinoma in older people in Taiwan.

PMID:
24392241
PMCID:
PMC3872443
DOI:
10.1155/2013/901987
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