Format

Send to

Choose Destination
See comment in PubMed Commons below
Psychiatry Res. 2014 Feb 28;215(2):488-90. doi: 10.1016/j.psychres.2013.12.017. Epub 2013 Dec 18.

COX-2 gene expression is correlated with cognitive function in recurrent depressive disorder.

Author information

1
Department of Adult Psychiatry, Medical University of Lodz, Aleksandrowska 159, 91-229 Lodz, Poland. Electronic address: galeckipiotr@wp.pl.
2
Department of Adult Psychiatry, Medical University of Lodz, Aleksandrowska 159, 91-229 Lodz, Poland.
3
Department of Medical Biochemistry, Medical University of Lodz, Lodz, Poland.

Abstract

Cyclooxygenase-2(COX-2) may be a key inflammatory enzyme involved in recurrent depressive disorder(rDD). In rDD group, COX-2 expression were higher and significant correlations occurred between COX-2 expression and cognitive functions. In controls there was no significant association between analysed variables. Thus, the COX-2 enzyme may be important for cognitive functioning in rDD.

KEYWORDS:

COX-2; Cognition; Depression

PMID:
24388097
DOI:
10.1016/j.psychres.2013.12.017
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center