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Clin Imaging. 2014 Mar-Apr;38(2):191-4. doi: 10.1016/j.clinimag.2013.11.015. Epub 2013 Dec 4.

Fulminant herpes simplex viral hepatitis: ultrasound and CT imaging appearance and a review of the imaging literature.

Author information

1
Medical Scientist Training Program, Duke University School of Medicine, Duke University Medical Center, Durham, NC, USA.
2
Department of Gastroenterology, Duke University Medical Center, Durham, NC, USA.
3
Department of Surgery, Duke University Medical Center, Durham, NC, USA.
4
Department of Radiology, Duke University Medical Center, Durham, NC, USA. Electronic address: lisa.ho@duke.edu.

Abstract

We report the case of a previously healthy 21-year-old woman who presented 6 days post-partum in acute fulminant hepatic failure. A liver ultrasound demonstrated normal echogenicity without discrete nodules while an enhanced computed tomography (CT) demonstrated innumerable 1- to 3-mm hypodense nodules throughout the liver with greater involvement of the left lobe. Liver biopsy confirmed herpes simplex virus infection. We believe this disease has a characteristic appearance on CT and prompt recognition can expedite diagnosis and therapy.

KEYWORDS:

Acute hepatitis; CT imaging; Herpes simplex virus; Ultrasound imaging

PMID:
24387920
DOI:
10.1016/j.clinimag.2013.11.015
[Indexed for MEDLINE]
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