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Chin J Cancer. 2014 Jan;33(1):32-9. doi: 10.5732/cjc.013.10207.

Standards of care and novel approaches in the management of glioblastoma multiforme.

Author information

1
Department of Clinical Neuroscience, Lausanne University Hospital, Lausanne 1011, Switzerland. andreas.hottinger@gmail.com.

Abstract

Glioblastoma multiforme (GBM) is the most common malignant primary brain tumor in adults. Standard therapeutic approaches provide modest improvement in the progression-free and overall survival, necessitating the investigation of novel therapies. We review the standard treatment options for GBM and evaluate the results obtained in clinical trials for promising novel approaches, including the inhibition of angiogenesis, targeted approaches against molecular pathways, immunotherapies, and local treatment with low voltage electric fields.

PMID:
24384238
PMCID:
PMC3905088
DOI:
10.5732/cjc.013.10207
[Indexed for MEDLINE]
Free PMC Article

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