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FEBS Lett. 1987 May 11;215(2):311-5.

Assignment of resonances for 'acute-phase' glycoproteins in high resolution proton NMR spectra of human blood plasma.

Abstract

Broad resonances at 2.04 and 2.08 ppm in 500 MHz Hahn spin-echo 1H NMR spectra of human blood plasma are assigned to the N-acetyl groups of mobile carbohydrate side-chains (largely N-acetylglucosamine and N-acetylneuraminic acid) of glycoproteins such as alpha 1-acid glycoprotein. Their intensities in spin-echo spectra correlate with clinical conditions in which an elevation of the level of 'acute-phase' glycoproteins is expected, and so may be of value in the study of certain diseases.

PMID:
2438159
DOI:
10.1016/0014-5793(87)80168-0
[Indexed for MEDLINE]
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