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Yeast. 2014 Feb;31(2):47-60. doi: 10.1002/yea.2997. Epub 2014 Jan 19.

Cryptococcus neoformans: historical curiosity to modern pathogen.

Author information

1
Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO, USA.

Abstract

The importance of the Basidiomycete Cryptococcus neoformans to human health has stimulated its development as an experimental model for both basic physiology and pathogenesis. We briefly review the history of this fascinating and versatile fungus, some notable aspects of its biology that contribute to virulence, and current tools available for its study.

KEYWORDS:

Cryptococcus gattii; Cryptococcus neoformans; capsule; cryptococcosis; meningitis; pathogenic fungus; yeast

PMID:
24375706
PMCID:
PMC3938112
DOI:
10.1002/yea.2997
[Indexed for MEDLINE]
Free PMC Article

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