Format

Send to

Choose Destination
Vet Dermatol. 2014 Feb;25(1):52-e21. doi: 10.1111/vde.12101. Epub 2013 Dec 28.

Cutaneous pythiosis in two dogs from Wisconsin, USA.

Author information

1
Department of Medical Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, WI, 53706, USA.

Abstract

BACKGROUND:

Pythium insidiosum is an oomycete that causes cutaneous lesions or infiltrative gastrointestinal disease in dogs, cats, humans, horses and other mammals, primarily in tropical and subtropical climates.

HYPOTHESIS/OBJECTIVES:

We report the clinicopathological findings associated with cutaneous pythiosis in two dogs from a Northern temperate climate zone.

ANIMALS:

A 3-year-old intact male Chesapeake Bay retriever was presented with an ulcerated soft-tissue swelling over the left eye. A 4-year-old spayed female German shepherd dog was presented with a soft-tissue swelling overlying the right hock. Both dogs lived in northern latitudes (between 43 and 45°N) and neither had travelled outside of Wisconsin or Michigan's upper peninsula, USA.

METHODS:

Histopathological examination and culture of affected tissues on specialized media, serology for anti-P. insidiosum antibodies, P. insidiosum-specific PCR and ribosomal RNA gene sequencing were carried out.

RESULTS:

Histopathological examination revealed pyogranulomatous and eosinophilic inflammation associated with wide, poorly septate hyphae.

CONCLUSIONS AND CLINICAL IMPORTANCE:

Even clinicians who practice in temperate climates should consider pythiosis as a differential diagnosis for young to middle-aged adult dogs presented with ulcerated cutaneous nodules or infiltrative gastrointestinal disease.

PMID:
24372864
DOI:
10.1111/vde.12101
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Wiley
Loading ...
Support Center