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Int J Biol Macromol. 2014 Mar;64:392-4. doi: 10.1016/j.ijbiomac.2013.12.031. Epub 2013 Dec 22.

Preparation and antibacterial activity of oligosaccharides derived from dandelion.

Author information

1
Microbiology Laboratory, The Second People's Hospital of Lianyungang, 41 East Hailian Road, Xinpu 222006, China. Electronic address: qianlilyg@163.com.
2
Microbiology Laboratory, The Second People's Hospital of Lianyungang, 41 East Hailian Road, Xinpu 222006, China. Electronic address: zhoulygsh@sina.com.
3
Geriatrics, The Second People's Hospital of Lianyungang, 41 East Hailian Road, Xinpu 222006, China.
4
Department of Nursing, The Second People's Hospital of Lianyungang, 41 East Hailian Road, Xinpu 222006, China.

Abstract

In this study, we prepared oligosaccharides from dandelion (Taraxacum officinale) by hydrolysis with hydrogen peroxide (H2O2) and investigated their antibacterial activity. The optimum hydrolysis conditions, as determined using the response surface methodology, were as follows: reaction time, 5.12h; reaction temperature, 65.53 °C and H2O2 concentration, 3.16%. Under these conditions, the maximum yield of the oligosaccharides reached 25.43%. The sugar content in the sample was 96.8%, and the average degree of polymerisation was approximately 9. The oligosaccharides showed high antibacterial activity against Escherichia coli, Bacillus subtilis and Staphylococcus aureus, indicating that dandelion-derived oligosaccharides have the potential to be used as antibacterial agents.

KEYWORDS:

Antibacterial activities; Dandelion-derived oligosaccharides; Hydrogen peroxide

PMID:
24368113
DOI:
10.1016/j.ijbiomac.2013.12.031
[Indexed for MEDLINE]

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