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Mol Cell Probes. 2014 Aug;28(4):138-40. doi: 10.1016/j.mcp.2013.12.003. Epub 2013 Dec 21.

Pertactin-negative variants of Bordetella pertussis in New York State: a retrospective analysis, 2004-2013.

Author information

1
Wadsworth Center, New York State Department of Health, PO Box 22002, Albany, NY 12201-2002, United States.
2
Emerging Infections Program, New York State Department of Health, Albany, NY 12237, United States.
3
Wadsworth Center, New York State Department of Health, PO Box 22002, Albany, NY 12201-2002, United States. Electronic address: halse@wadsworth.org.

Abstract

The first report of pertactin-negative variants of Bordetella pertussis in the United States has raised questions about the role of acellular pertussis vaccines in the recent increase of pertussis cases. Our laboratory utilized a sequence-based method to identify mutations in the pertactin gene responsible for these variants and assessed vaccination status from the associated cases.

KEYWORDS:

Acellular vaccine; Bordetella pertussis; Pertactin-negative variants

PMID:
24365130
DOI:
10.1016/j.mcp.2013.12.003
[Indexed for MEDLINE]

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